It's also the first Grand Slam tournament that Maria Sharapova is able to play in since coming off her suspension after the 2016 Australian Open for violation of the anti-doping policy.
One of the favorites in this year's US Open to no one's surprise is Venus Williams. She's appeared in the Australian and Wimbledon finals this year and if she makes it to and wins the US Open, she will reclaim the world number one ranking for the first time since July 2002
The sixth seeded Kerber wasn't the only big name that fell in the US Open women's tournament's first round. Number 7 seeded Johanna Konta, number 2 seed Simona Halep, number 14 seeded Kristina Mladenovic, number 19 Anastasia Pavlyuchenkova, 21st seeded Ana Konjuh, 24th seeded Kiki Bertens, 26 seeded Anett Kontaveit, 28 seeded Lesia Tsurenko and 32 seeded Lauren Davis all fell in the opening round
Venus beat Dodin in straight sets 7-5, 6-4 to advance to her third round match against Greece's Maria Sakkari.
The winner of this match will face in the fourth round the winner of the clash between Ekaterina Makarova and Carla Suarez Navarro.
Will Venus finally claim a Grand Slam title this year? We'll just have to wait and see.